Technology for evidence-based skincare and aesthetics
DermaSci turns complex skin science into personalized, evidence-based guidance for skincare products and in-clinic treatments.
Why DermaSci exists
The skin is a living, dynamic organ. Every visible change reflects overlapping processes at the cellular and molecular level: signalling, inflammation, barrier function, pigment production, vascular activity, collagen synthesis and the microbiome itself.
Nobody can reasonably evaluate that complexity while standing in a store, browsing products online or listening to their favourite influencer. Marketing overstates what products do, and people are exhausted with decision fatigue.
Clinics offering increasingly technical procedures face a similar problem at the consultation stage: a confused client is unlikely to proceed, and the opportunity is lost.
The result is a population of confused, distrustful consumers and clinics who cannot get or keep clients.
The Engine
An engine that helps people and clinicians achieve clarity about the right products, the best routines, and the most effective in-clinic treatments and procedures, in the best order and at the right time.
This is not a language model prompted to answer skincare questions, and it is not a chatbot about procedures. It is a defined, auditable protocol, and it improves as it is used.
Our rating scale
Every ingredient and procedure carries an evidence level and the recommendation it supports. When the science is strong we say so, and when it is early or unsettled we say that too. We do not average conflicting findings into a false middle.
One engine, two approaches
A personalized, evidence-based companion that helps people understand their skin and act on it with confidence.
Our clinic platform will meaningfully improve consultation quality for all levels of staff, standardize and harmonize treatment plans, increase credibility and achieve better client retention. Talk to us about how our platform could transform your practice.
If you are tired of undercutting prices and the race to the bottom, we can help.
Working with DermaSci
We work with clinics, clinical and scientific collaborators and aligned brands that share a commitment to evidence and to raising the standard of skincare and aesthetic care. We are selective, and we hold every partnership to the same evidentiary standard as everything we build.
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Research
PhD-level scientific commentary on the mechanisms, evidence, and clinical implications of modern aesthetic medicine. Updated with 2018–2026 primary literature.
Why the most sophisticated aesthetic outcomes today look like nothing happened at all, and what the current science tells us about how to achieve them
There is a particular kind of face that stops you, not because it is dramatically altered, but because it appears immune to the passage of time without any visible explanation.
Source: Photo by Andrea Piacquadio.
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Figure 1. Representative images of dermal fibroblasts. Fibroblasts in 2D (A) and 3D (B) culture observed by light microscopy. Fibroblast in culture (C) and in healthy skin (D), observed by transmission electron microscopy. Fibroblast in culture observed by atomic force microscopy (E) and by confocal microscopy (F). Images are from authors' laboratory. Ref: https://doi.org/10.3390/biomedicines12071586
How collagen synthesis works at the molecular level, and what the current science tells us about how to restart it.
If you want to understand why skin ages, you must understand the fibroblast. This spindle-shaped mesenchymal cell is the primary manufacturer of the extracellular matrix, the biological scaffold that gives your skin its structure, resilience, and volume.
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Biostimulants: A Clinical Comparison
Photo by cottonbro studio.
Biostimulants are a different category of injectable, not merely a different product. They do not fill a space. They instruct the biology of the dermis to rebuild one.
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Photo by Youssef Labib.
Exosomes are everywhere in aesthetic medicine in 2026. The biology is genuinely interesting. The gap between what the science supports and what is being marketed is, however, substantial.
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AGA biology, melanocyte stem cell decline, the connection to PRP, and what a physician's clinical observation is telling us about where exosome science is heading
A Clinical Observation That Deserves a Scientific Answer\nA clinic physician recently reported an observation that stopped the conversation: patients receiving plant-derived exosome scalp treatments in combination with PRP were showing a reduction in white hair. Not in all patients. Not dramatically in every case. But consistently enough, and visibly enough at trichoscopic magnification, that she noticed it, flagged it, and asked whether the science could explain it.
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